Integrated hardware/software interface enables productive workflow between light and electron microscopes for the first time

Carl Zeiss have introduced a unique hardware/ software interface to connect light and scanning electron microscopes for correlative microscopy in the life sciences. The “Shuttle & Find” interface enables users to recall regions of interest in fixed specimens in an electron microscope, which were previously identified in a light microscope and vice versa. The entire process takes only a few seconds. This opens up totally new dimensions in microscopy: rapid and precise overlay of light and electron microscope images, high-resolution magnification of the details, and the merger of functional and structural information.



The key elements of Shuttle & Find for correlative light and electron microscopy (CLEM) are:

• a transferable specimen holder that enables smooth specimen transfer between the light and electron microscopes (shuttle) and
• a software module that controls all functions of light and electron microscopes needed to identify and recall the defined region of interest (Find)

Learn more about Shuttle & Find